Desyrel ģ

Generic Name: Trazodone (TRAZ-oh-dohn)

Drug Class: Antidepressant, Miscellaneous


Drug Uses

This medicine is used to treat all types of depression. Other accepted uses are reducing the symptoms of agoraphobia, help in drug-induced insomnia, can be used in combination therapy of some pain syndromes. Your doctor may use this medicine to treat other conditions.

General Information

This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your health care provider.

How it Works

This medicine helps relieve depression by increasing the amount of a chemical called serotonin in brain centers.

How to Take It

This medicine should be taken with food and the tablet can be crushed. If it causes excessive drowsiness or dizziness the larger portion of it should be taken at bedtime and the rest should be divided into two or three doses for the day usage.

Possible Side Effects

    • drowsiness or lightheadedness

    • weight gain

    • dry mouth

    • constipation

    • A rare side effect causing a sustained painful erection in males (priaprism) has occurred. If you experience this, talk to your doctor immediately.

    • If you experience other bothersome side effects, contact your health care provider.


    • Talk to your doctor before you take this medicine if you have; a history of heart disease, epilepsy, alcoholism, liver or kidney disease, or if you are having general anesthesia.

    • Alcohol can add to the side effects of this medicine and should be avoided.

    • This medicine causes dizziness or drowsiness. Do NOT drive, and restrict activities until you know how this medicine will affect you.

    • A rare side effect causing a prolonged painful erection in males (priaprism) has occurred. If you experience this, stop taking the drug and contact your healthcare provider immediately.


    • Seek medical attention immediately. For non emergencies, contact your local or regional poison control center at 1-800-222-1222.

Drug Interactions

    • This medicine may increase the affects antihypertensive drugs, drugs with sedative effects, phenytoin (Dilantin) or fosphenytoin (Celebyx) and tramadol (Ultram).

Missed Dose

Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.


Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.


If you are pregnant or thinking of becoming pregnant talk to doctor about the risk versus the benefits of taking this medicine. This medicine has been found in breast milk so it is advised not to use this medicine while breast-feeding.

More Information

While taking this medicine it is advised to avoid using St. Johnís Wort, ginseng, ma huang, Indian snakeroot and yohimbe. It is also advised to talk to your doctor or pharmacist before taking any herbals with this medicine.

Copyright © 2004 PharmClips, Inc. All rights reserved. Information expires March 1, 2005. Published March 1, 2004.

This information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This is general information and should not in any event be construed as specific instructions for individual patients. The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. The reader is advised to check with their health care provider before making any changes in their drug regimen.

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